The Francis Crick Institute

Contract:         Fixed-term, 3 years

An exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovation and science.  A postdoctoral research post in the laboratory of Samra Turajlic (Cancer Dynamics, https://www.crick.ac.uk/research/labs/samra-turajlic) is now available. We are seeking a collaborative
and self-motivated post-doctoral bioinformatician to work on an exciting tumour evolution project, collaborating with a network of groups across The Francis Crick Institute, UCL Cancer Institute and the Institute of Cancer Reserach. The position will involve analysis of data from large-scale tumour evolutionary trials such as the TRACERx and PEACE studies. These studies have made a wide number of successful contributions to the field of tumour evolution and achieved an excellent track record of high impact output. This project sits at the interface of basic and translational research, and will be utilising a rich multi-omic dataset (bulk and single cell) generated from patient tumour samples, from large-scale trials run locally. The role is ideally suited for a creative individual with a strong interest in cancer genomics, cancer evolution, evolutionary biology, and software / pipeline development in a leading academic setting.

The successful applicant will have a proven track record in cancer bioinformatics, with previous experience of NGS data analysis, be fluent in at least one of the following programming languages: Python or R, and is expected to have strong skills in either: genomics, cancer biology or evolution. Prior experience with data analysis based on integrating large datasets is particularly desired. The position will be based within a multi-disciplinary team of cancer evolutionary biologists, wet-lab scientists and translational research clinicians concerned with both basic evolutionary principles and application of evolutionary rules in the clinic. The lab also has a strong focus on understanding anti-tumour immune response. The applicant will have opportunity to develop collaborations nationally and internationally, and there will be an opportunity to engage with our industry and academic partners. The candidate will work closely with other computational scientists at Francis Crick Institute and have ample opportunities to develop their skills. A comprehensive computational infrastructure is available, with access to multiple HPC clusters.

About us 

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply via our website.
• The closing date for applications is 15 March 2021 at 23:59.
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.