Post Doctoral Researcher

Job Overview

Location
Cork, Munster
Job Type
Full Time
Date Posted
2 months ago

Additional Details

Job ID
5511
Job Views
35

Job Description

University College Cork - Department of Pathology

Location:Cork - Ireland
Salary:€37,873 to €45,041 or £31,945.88 to £37,992.08 (converted salary*) p.a. (IUA Salary Scale)
Hours:Full Time
Contract Type:Fixed-Term/Contract
Placed On:1st September 2020
Closes:25th September 2020


48-month, fixed-term, whole-time post

Position summary

This position is within the Departments of Pathology, the School of Microbiology, and the APC Microbiome Ireland. The Post-Doctoral Researcher will build on existing work on bacterial microcompartment proteins in E. coli to clone and characterise novel microcompartment constructs of therapeutic potential. Model assays for small molecule interference with microcompartment assembly will be developed. RT-PCR analysis of microcompartment gene expression in uropathogenic E. coli will also be carried out, with in vitro competition studies of key gene knockouts against wild type.

APC Microbiome Ireland is a trans-disciplinary research centre, with clinicians, clinician-scientists and basic scientists from diverse backgrounds working in teams, sharing ideas and resources. Although focused upon the gastrointestinal bacterial community (the microbiota), the scale and scope of the work has become one of the fastest moving areas of biology. The microbiota is not only a target for treatment and prevention of disease, it is a repository for functional food ingredients and even new drugs and is a source of novel biomarkers of disease risk. The scientific organisation of the APC consists of a matrix of ‘spokes’ or themes of intellectual pursuit which are supported by multiple horizontal or shared technology platforms.

Qualifications/experience

The ideal candidate should have:

  • A PhD in or on a relatable microbiological field.
  • A skillset of protein expression and laboratory microbiology techniques.
  • Experience with molecular/synthetic biology including gene cloning and knockout.
  • Experience with electron microscopy
  • Experience with Nucleic acid extraction from clinical samples (urine), RT-PCR, NGS library preparation.
  • Proven ability to design, manage and conduct independent research to a high level.

Post Duration: 48 Months

Project Title: Bacterial Microcompartment Engineering: building them up and knocking them down

For an information package including further details of the post see ore.ucc.ie.

Informal enquiries can be made in confidence to Professor Michael Prentice, Email: [email protected].

Applications must be submitted online via the University College Cork vacancy portal (ore.ucc.ie). Queries relating to the online application process should be referred to [email protected], quoting the job-title and project name.

Candidates should apply, in confidence, before 12 noon (Irish Local Time) on Friday, 25th September 2020.

No late applications will be accepted.

University College Cork is an equal opportunities employer

Please note that an appointment to posts advertised will be dependent on University approval, together with the terms of the employment control framework for the higher education sector.

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