PhD Studentship: Unravelling the Relationship between RNA Modification and RNA Structure in RNA Mobility (DING_JDTP2)

Job Overview

Location
Norwich, England
Job Type
Full Time
Date Posted
7 days ago

Additional Details

Job ID
6252
Job Views
12

Job Description

University of East Anglia - School of Biological Sciences

Qualification Type:PhD
Location:Norwich
Funding for:UK Students, EU Students, International Students
Funding amount:£15,285 per year and a Research Training Support Grant for each year of the studentship of £5,000 p.a..
Hours:Full Time
Placed On:15th October 2020
Closes:23rd November 2020


Start date: 1 Oct 2021 

Supervisor:  Dr Yliliang Ding

Project description: 

RNA plays crucial roles in living cells, ranging from metabolite sensing, signaling, transcription, RNA processing to translation. Its function is determined by its sequence and structure. Structure can be perturbed by several factors, including modifications, a well known example being methylation. RNA structure can thus encodes another layer of information besides the genetic code which can influence every step in the gene expression program as well as RNA signaling functions.

Despite its key roles, we know very little about RNA structure and how it relates to function. This project aims to uncover the structure of mRNA using cutting-edge in vivo structure probing technologies coupled with advanced computational approaches, including deep learning.

This project will involve a broad range of training opportunities across multiple disciplines including genomics bioinformatics, systems biology, biophysics, computational biology and nucleic acid chemistry. If you have a background in biochemistry, biology, chemistry, computer science or physics and are interested in RNA, structure, shape, computation and/or technology and method development, this PhD might be for you. Please contact us to find out more.

About NRP DTP:

The Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) is open to UK and international candidates for entry October 2021 and offers postgraduates the opportunity to undertake a 4-year PhD research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship placement (PIPS) during their study. The placement offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second class honours degree, or equivalent, are invited to apply.

This project has been shortlisted for funding by the NRPDTP programme. Shortlisted applicants will be interviewed on Thursday 7th January, Friday 8th January and Monday 11th January 2021.

Visit our website for further information on eligibility and how to apply: https://biodtp.norwichresearchpark.ac.uk/

Our partners value diverse and inclusive work environments that are positive and supportive. Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background.

Person Specification: 

At least UK equivalence Bachelors (Honours) 2:1 or UK equivalence Master's degree. English Language requirement (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category).

Funding notes: 

This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD studentship. The studentship includes payment of tuition fees (directly to the University), a stipend for each year of the studentship (2020/21 stipend rate: £15,285), and a Research Training Support Grant for each year of the studentship of £5,000 p.a..

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